Catherine Dubernet Selected Research

4-(N)-tris-nor-qualenoyl-gemcitabine

11/2008	Squalenoyl nanomedicine of gemcitabine is more potent after oral administration in leukemia-bearing rats: study of mechanisms.
8/2008	Squalenoylation favorably modifies the in vivo pharmacokinetics and biodistribution of gemcitabine in mice.
12/2007	A new nanomedicine of gemcitabine displays enhanced anticancer activity in sensitive and resistant leukemia types.

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Catherine Dubernet Research Topics

Disease

10	Neoplasms (Cancer) 11/2011 - 09/2002
3	Leukemia 11/2008 - 11/2006
2	Experimental Leukemia 08/2008 - 11/2006
1	Large Granular Lymphocytic Leukemia 11/2008
1	Neoplasm Metastasis (Metastasis) 11/2008
1	Weight Loss (Weight Reduction) 05/2008
1	Leukemia L1210 12/2007
1	Hyperthermia 09/2005
1	Hepatocellular Carcinoma (Hepatoma) 05/2005
1	Carcinoma (Carcinomatosis) 09/2004
1	Virus Diseases (Viral Diseases) 04/2004

Drug/Important Bio-Agent (IBA)

4	Gemcitabine FDA Link 11/2008 - 11/2006
3	4-(N)-tris-nor-qualenoyl-gemcitabineIBA 11/2008 - 12/2007
2	Pharmaceutical PreparationsIBA 11/2011 - 11/2008
2	NucleosidesIBA 08/2008 - 12/2007
2	Folic Acid (Vitamin M)FDA LinkGeneric 09/2005 - 09/2004
1	Cytidine DeaminaseIBA 11/2008
1	polyisohexylcyanoacrylateIBA 05/2005
1	Doxorubicin (Adriamycin)FDA LinkGeneric 05/2005
1	Drug CarriersIBA 09/2004
1	rhodamine BIBA 09/2004
1	Ethylene Glycol (Monoethylene Glycol)IBA 09/2004
1	beta-CyclodextrinsIBA 09/2004
1	Antisense OligonucleotidesIBA 04/2004
1	OligonucleotidesIBA 09/2002

Therapy/Procedure

2	Oral Administration 11/2008 - 11/2006
1	Injections 05/2008
1	Therapeutics 09/2002